Thermo Scientific Exactive Orbitrap LC-MS/MS

Exactive Orbitrap LC-MS/MS from Thermo Scientific

Ref: st4256


12 month On-Site Warranty (UK)


£ Please Call

This Exactive Orbitrap LC-MS supports screening applications, from routine compound identification to the most demanding analysis of trace levels components in complex mixtures. In addition, it allows an alternate positive-negative scan mode of operation.

Are you an academic organisation? This system applies for a University discount
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System Details

Download Calibration Data for Micromass Premier XE

Powered by patented Orbitrap technology, this Exactive™ mass spectrometer has been fully re-conditioned at our lab facility here in the UK. It provides fast, sensitive, reliable, and confident detection and identification of compounds in complex mixtures, while maintaining full compatibility with U-HPLC and fast chromatography - see calibration report above.

The upgraded HCD collision cell adds more functionality to the benchtop system by providing 'All Ion Fragmentation' while maintaining high resolution, accurate mass and high sensitivity, making it ideal for:

  • Food Safety
  • Environmental
  • Clinical Research
  • Forensic Toxicology
  • Drug Discovery
  • Exact mass measurements of organic compounds
  • Early drug discovery metabolism and pharmokinetics (DMPK)
  • General unknown screening
  • Multiple residue analysis (Pesticides, Mycotoxins, veterinary drugs)
  • Metabolomics

Key Benefits

  • Routine FT mass accuracy
  • Resolutions of up to 100,000 at 1 Hz scan cycle
  • Maximum scan speed of 10 Hz
  • Dynamic range of > 4,000 (intra-scan)
  • Full scan MS analysis
  • 'All Ion Fragmentation' with multiple dissociation techniques: Source CID (Collisional Induced Dissociation) and HCD (Higher Energy Collisional Dissociation)

Features and Specification

  • Easy to operate
  • Mass resolutions of up to 100,000 at m/z 200 at a scan rate of 1 Hz, minimum resolution 10,000 at m/z 200 at a scan rate of 10 Hz
  • Mass accuracy: < 5 ppm with external calibration, < 2 ppm using internal calibration
  • Mass range m/z 60-4,000
  • Scan speeds up to 10 Hz
  • Polarity Switching: One full cycle in < 1 sec (one full scan positive mode and one full scan negative mode at resolution setting of 10,000)
  • Sensitivity: A flow injection of 500 fg of Buspirone giving a S/N of better than 10:1 for the selected mass chromatogram of the [M+H]+ ion (m/z = 386.2551)
  • Dynamic Range: > 4,000 within a single scan with guaranteed specified mass accuracy
  • MS Scan Power: Full scan and "All Ion Fragmentation" by HCD
  • Scan rate: 1 - 10 Hz
  • High in-scan dynamic range (4 orders of magnitude)
  • Mass accuracies of better than 2ppm in full scan and 'All Ion Fragmentation' mode
  • Fast polarity switching (full cycle of 1 positive and 1 negative scan within 1 second)

View the manufacturers specification

System Includes

  • Thermo Scientific Exactive Orbitrap LC-MS with HCD Upgrade
  • Thermo Accela Quaternary Pump
  • Thermo CTC PAL Autosampler with C72 cheminert UHPLC valve and 1 x cooled stack
  • Temperature controller for CTC stack
  • Thermo Fusion 100T syringe pump
  • Leybold Sogevac SV40 BI Roughing Pump
  • PC with TFT screen and Xcalibur 2.2 data system installed
  • Cables & electronic manuals
  • Installation
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Servicing & Maintenance

As a continually expanding company Jaytee have a great deal to offer, from service agreements to total instrument portfolio management. Since each client has different requirements, we are able to provide tailored service agreements, whether it be on the instruments you purchase from us, or your own equipment.


Jaytee has developed its calibration policy in line with the marketplace and offers a wide range of calibration services. Our clients often require instrument PQ/validation, so we offer a unique approach to this, providing our own calibration package that is specific to your needs.

Enquire / Get A Quote

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Contact Information

Jaytee Biosciences Ltd,
Altira Business Park,
Herne Bay, Kent, CT6 6GZ.

Phone: +44 (0) 1227 265333

Email: Mailto sales jaytee

Why employ ms4sale?

Your MS options are far reaching, so why use Jaytee Biosciences? Unlike other providers of used MS equipment, we have the ability to completely:

This is because we employ both skilled engineers and experienced scientists, which allows us to provide a value added solution.

When we acquire an MS system, we are not simply re-listing for sale with a mark-up. We service,test and run the system, producing chromatographic and mass spectral data before we advertise. When our clients ask us whether a particular system is suitable for their application, we provide detailed information, and offer a pre-visit service whereby you send us your sample, which we run and prove for your benefit. Why? Because we can, and because it helps you make the right choices.

Ask yourself why other companies are only showing stock images, with no data or proof of performance - because we have the skills, you get the peace of mind and the ongoing support for your method.

Finally, this is at no added cost, since our pricing policy is flexible, and therefore competitive - a win/win!

Jaytee; No take overs/mergers in over 35 years - just professional, solid, skilled on going support.